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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCPEP1 All Species: 20.61
Human Site: S280 Identified Species: 30.22
UniProt: Q9HB40 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB40 NP_067639.1 452 50831 S280 L T K S T P T S T M E S S L E
Chimpanzee Pan troglodytes XP_001172174 452 50766 S280 L T K S T P T S T M E S S L E
Rhesus Macaque Macaca mulatta XP_001104815 452 50613 S280 L T K S T P T S T V E S S L E
Dog Lupus familis XP_537688 477 53125 S305 L T K S T P T S A M K S S L E
Cat Felis silvestris
Mouse Mus musculus Q920A5 452 50948 K280 L T K S S P E K A M E S S L E
Rat Rattus norvegicus Q920A6 452 51156 T280 L T K S T P D T S M E S S L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521733 560 62210 S386 L T K T P E T S A K K T S P E
Chicken Gallus gallus NP_001012821 446 49959 K270 T K E V P E M K A D E Q E N F
Frog Xenopus laevis NP_001088737 443 49367 R273 F A G K T D Q R S P E F G K A
Zebra Danio Brachydanio rerio NP_956486 445 49600 M273 L T Q N S D E M V K S S A D Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392686 435 48876 G273 L T R M E A S G T R S L A E R
Nematode Worm Caenorhab. elegans NP_872130 445 50095 D271 L K K G D T D D W S S S A M R
Sea Urchin Strong. purpuratus XP_785691 470 52220 G278 F H Y T C C G G V N D S V Y S
Poplar Tree Populus trichocarpa XP_002313552 489 53783 D285 F L L D S G S D P L S L T T A
Maize Zea mays NP_001148149 464 50034 D279 L K D E A S G D A T A T A T A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67Y83 461 51734 P279 L L D T G M D P V S L T T S L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96 82.8 N.A. 82 82.7 N.A. 60.7 65.9 65.9 62.8 N.A. N.A. 42 41.8 47.8
Protein Similarity: 100 99.3 99.1 88.2 N.A. 90.7 91.8 N.A. 70.7 78.9 77.2 77.6 N.A. N.A. 59.2 58.6 63.6
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 80 N.A. 46.6 6.6 13.3 20 N.A. N.A. 20 20 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 80 93.3 N.A. 66.6 13.3 20 53.3 N.A. N.A. 40 33.3 20
Percent
Protein Identity: 42.7 45 N.A. 42.9 N.A. N.A.
Protein Similarity: 57.2 58.6 N.A. 60.7 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 26.6 20 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 7 0 0 32 0 7 0 25 0 19 % A
% Cys: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 7 7 13 19 19 0 7 7 0 0 7 0 % D
% Glu: 0 0 7 7 7 13 13 0 0 0 44 0 7 7 44 % E
% Phe: 19 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % F
% Gly: 0 0 7 7 7 7 13 13 0 0 0 0 7 0 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 19 50 7 0 0 0 13 0 13 13 0 0 7 0 % K
% Leu: 75 13 7 0 0 0 0 0 0 7 7 13 0 38 7 % L
% Met: 0 0 0 7 0 7 7 7 0 32 0 0 0 7 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 7 0 0 0 7 0 % N
% Pro: 0 0 0 0 13 38 0 7 7 7 0 0 0 7 0 % P
% Gln: 0 0 7 0 0 0 7 0 0 0 0 7 0 0 7 % Q
% Arg: 0 0 7 0 0 0 0 7 0 7 0 0 0 0 13 % R
% Ser: 0 0 0 38 19 7 13 32 13 13 25 57 44 7 7 % S
% Thr: 7 57 0 19 38 7 32 7 25 7 0 19 13 13 0 % T
% Val: 0 0 0 7 0 0 0 0 19 7 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _